Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 4 , Pages 414-416, December 2007

Twin Pregnancy with Gastroschisis in Both Twins

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital–Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan

Accepted 6 June 2007.

Article Outline

SUMMARY 

Objective

Gastroschisis is a congenital malformation characterized by an abdominal wall defect located laterally to a normal umbilicus. The cause of gastroschisis is unknown, but most authors consider it exogenous. We describe the case of a woman with a twin pregnancy in which both twins had gastroschisis.

Case Report

A 17-year-old primiparous female was referred to our institution because of a twin pregnancy, with one twin diagnosed with gastroschisis at 34 weeks of gestation. Unfortunately, gastroschisis was noted in both twins, but no other anomalies were observed under level II sonographic evaluation. The twins were delivered by cesarean section at 36+weeks of gestation because of preterm labor and breech presentation of one fetus. Both twins presented with a 3-cm abdominal wall defect located to the right side of the umbilicus and a large portion of the bowel protruding that was not covered by membrane. Histopathology of the placenta revealed that the twins were diamniotic monochorionic. Chromosomal analysis of cord blood showed normal karyotype (46, XX) in both newborns.

Conclusion

The cause of gastroschisis is unknown, although possible exogenous causes have been studied. The diagnosis of gastroschisis in twin pregnancy is always in late gestation. Therefore, maternal serum alpha feto-protein screening and a detailed prenatal ultrasound evaluation are recommended in multifetal pregnancies.

Key Words:  gastroschisis , maternal serum alpha fetoprotein , twins

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PII: S1028-4559(08)60013-3

doi:10.1016/S1028-4559(08)60013-3

Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 4 , Pages 414-416, December 2007

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