« Previous
Next »
Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 1
, Pages 26-32
, March 2007
Molecular Carcinogenesis of Endometrial Cancer
References
- . A population-based study of endometrial cancer and familial risk in younger women: Cancer and Steroid Hormone Study Group . Cancer Epidemiol Biomarkers Prev . 1996;5:411–417
- . Two pathogenetic types of endometrial carcinoma . Gynecol Oncol . 1983;15:10–17
- Case-control study of endogenous steroid hormones and endometrial cancer . J Natl Cancer Inst . 1996;88:1127–1135
- . Comparison of estrogen and progesterone receptor, Ki67, and p53 immunoreactivity in uterine endometrioid carcinoma and endometrioid carcinoma with squamous, mucinous, secretory, and ciliated cell differentiation . Hum Pathol . 1998;29:924–931
- . p53 in endometrial cancer and its putative precursors: evidence for diverse pathways of tumorogenesis . Hum Pathol . 1995;26:1268–1274
- . Endometrial intraepithelial carcinoma: a distinctive lesion specifically associated with tumors displaying serous differentiation . Hum Pathol . 1995;26:1260–1267
- . Clear cell carcinoma of the endometrium is characterized by a distinctive profile of p53, Ki-67, estrogen, and progesterone receptor expression . Hum Pathol . 1998;29:551–558
- . Pten, a protean tumor suppressor . Am J Pathol . 2001;158:1895–1898
- . PTEN signaling pathways in melanoma . Oncogene . 2003;22:3113–3122
- Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers . J Natl Cancer Inst . 2000;92:924–930
- PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma . Int J Cancer . 2001;91:22–26
- . PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics . Clin Cancer Res . 1998;4:3005–3010
- . Microsatellite instability in endometrial carcinoma . Oncogene . 1994;9:1163–1166
- . Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma . Am J Pathol . 1996;148:1671–1678
- . Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas . Cancer Res . 2000;60:1750–1752
- . MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas . Oncogene . 1998;17:2413–2417
- Methylation of hMLH1 in a population-based series of endometrial carcinomas . Clin Cancer Res . 2000;6:3607–3613
- . Altered expression of hMLH1 and hMSH2 protein in endometrial carcinomas with microsatellite instability . Hum Pathol . 2000;31:354–358
- Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study . Clin Cancer Res . 2002;8:138–143
- Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas . Cancer Res . 1995;55:5556–5560
-
Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers
.
Proc Natl Acad Sci USA
. 2003;100:5908–5913
- . Favorable survival associated with microsatellite instability in endometrioid endometrial cancers . Obstet Gynecol . 2001;97:417–422
- . Mutations of the Ki-ras oncogene in carcinoma of the endometrium . Am J Pathol . 1995;146:182–188
- . K-ras exon 2 point mutations in human endometrial cancer . Cancer Lett . 2001;164:207–212
- Mutation of the Ki-ras protooncogene in human endometrial hyperplasia and carcinoma . Cancer Res . 1993;53:1906–1910
- . K-ras mutation in endometrial carcinoma with microsatellite instability . J Pathol . 2001;193:193–199
- . Anticorresponding mutations of the KRAS and PTEN genes in human endometrial cancer . Oncol Res . 2000;7:567–570
- . Betacatenin mutations and aberrant nuclear expression during endometrial tumorigenesis . Br J Cancer . 2001;84:209–217
- . The Wnt signaling pathway in development and disease . Annu Rev Cell Dev Biol . 2004;20:781–810
- . Betaand gamma-catenin expression in endometrial carcinoma. Relationship with clinicopathological features and microsatellite instability . Virchows Arch . 2001;438:464–469
- . The role of cancer cell motility in invasion . Cancer Metastasis Rev . 1984;3:127–141
- . Motility and adhesive properties of high and low-metastatic murine neoplastic cells . Cancer Res . 1984;44:811–824
- . E-cadherin expression in endometrioid, papillary serous, and clear cell carcinoma of the endometrium . Obstet Gynecol . 2002;100:1290–1295
- Prognostic significance of E-cadherin protein expression in pathological stage I–III endometrial cancer . Clin Cancer Res . 2004;10:5546–5553
- . Combined E-cadherin, alpha-catenin, and beta-catenin expression is a favorable prognostic factor in endometrial carcinoma . Int J Gynecol Cancer . 2006;16:1379–1385
- . Loss of nuclear p16 protein expression is not associated with promoter methylation but defines a subgroup of aggressive endometrial carcinomas with poor prognosis . Clin Cancer Res . 2000;6:153–159
- . P16/MTS1 and pRB expression in endometrial carcinomas . Virchows Arch . 1999;434:23–28
- . The role of p16-cyclin d/CDK-pRb pathway in the tumorigenesis of endometrioid-type endometrial carcinoma . Br J Cancer . 2000;82:675–682
- Hypermethyltion in the p16 promoter region in the carcinogenesis of endometrial cancer in Japanese patients . Anticancer Res . 2006;26:851–856
- Low frequency of BRAF and CDKN2A mutations in endometrial cancer . Int J Cancer . 2005;115:930–934
- . The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways . Cancer . 2000;88:814–824
- . Distinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumorigenesis . Cancer . 2002;94:2369–2379
- . Correlation of proliferation indices, apoptosis, and related oncogene expression (bcl-2 and c-erbB-2) and p53 in proliferative, hyperplastic, and malignant endometrium . Hum Pathol . 1998;29:1150–1159
- . Fluorescence in situ hybridization analysis of FER2/neu, c-myc, and p53 in endometrial cancer . Exp Mol Pathol . 1999;67:135–143
- Molecular pathology of endometrial hyperplasia and carcinoma . Hum Pathol . 2001;32:569–577
- . Molecular genetic pathways in various types of endometrioid carcinoma: from a phenotypical to a molecularbased classification . Virchows Arch . 2004;444:213–223
-
KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2
.
Science (Washington DC)
. 1995;268:884–886
- KAI1 metastasis suppressor protein is down-regulated during the progression of human endometrial cancer . Clin Cancer Res . 2003;9:1393–1398
- Loss of Smad4 protein expression occurs infrequently in endometrial carcinomas . Int J Gynecol Pathol . 2003;22:347–352
- . TGF-beta signaling is disrupted in endometrioid-type endometrial carcinomas . Gynecol Oncol . 2004;95:173–180
- . p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis . Am J Pathol . 1997;150:177–185
- Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies . Cancer Res . 1997;57:3935–3940
- . Microsatellite instability is uncommon in uterine serous carcinoma . Am J Pathol . 1997;150:75–79
- . Microsatellite instability in endometrial carcinomas: clinicopathologic correlations in a series of 42 cases . Hum Pathol . 1998;29:1160–1164
- . Comparative immunohistochemical study of endometrioid and serous papillary carcinoma of endometrium . Eur J Gynaecol Oncol . 2001;22:122–126
- . HER-2/neu amplification and overexpression in endometrial carcinoma . Int J Gynecol Pathol . 1999;18:138–143
- Abnormalities of Eand P-cadherin and catenin (beta-, gamma-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia . J Pathol . 2003;199:471–478
- . Beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtype . Mod Pathol . 2002;15:1032–1037
-
.
Molecular genetic analysis of endometrial carcinoma: evidence for 2 genetically distinctive entities
.
Virchows Arch
. 2001;439:247–252
- . p53 mutation is infrequent in clear cell carcinoma of the ovary . Gynecol Oncol . 2001;80:189–193
- Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer . Clin Cancer Res . 2005;11:6422–6430
- Frequent hypermethylation of MLH1 promoter in normal endometrium of patients with endometrial cancers . Oncogene . 2003;22:2352–2360
- Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review . Gastroenterology . 1993;104:1535–1549
- . The risk of endometrial cancer in hereditary nonpolyposis colorectal cancer . Am J Med . 1994;96:516–520
- The epidemiology of endometrial cancer in hereditary nonpolyposis colorectal cancer . Anticancer Res . 1994;14:1675–1678
- . The International Collaborative Group on HNPCC. Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study . Gastroenterology . 1997;113:1146–1158
- Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer . Nat Genet . 1997;17:271–272
- Lack of MSH2 and MSH6 characterizes endometrial but not colon carcinomas in hereditary nonpolyposis colorectal cancer . Cancer Res . 2001;61:2813–2815
- Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: association with family history and histopathology . Int J Cancer . 2000;86:60–66
- Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumors from HNPCC patients . J Pathol . 2000;192:328–335
- . Familial endometrial adenocarcinoma . Clin Obstet Gynecol . 1998;41:167–171
- Molecular analysis of familial endometrial carcinoma: a manifestation of hereditary nonpolyposis colorectal cancer or a separate syndrome? . J Clin Oncol . 2005;23:4609–4616
- Microarray analysis reveals distinct gene expression profiles among different histologic types of endometrial cancer . Cancer Res . 2003;63:6–11
PII: S1028-4559(08)60102-3
doi: 10.1016/S1028-4559(08)60102-3
© 2007 Taiwan Association of Obstetric & Gynecology. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 1
, Pages 26-32
, March 2007
