Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 1 , Pages 47-49, March 2007

Preliminary Descriptive Statistics of the Taiwanese Registry of Epilepsy and Pregnancy for the First 2 Years

  • Tung-Yao Chang

      Affiliations

    • Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
    • Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Tung-Yao Chang, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, 92, Section 2, Chung-Shan North Road, Taipei 104, Taiwan
    • ,
  • Chi-Wan Lai

      Affiliations

    • Department of Neurology, Sun Yat-Sen Cancer Center, Taipei, Taiwan
    • ,
  • Hsiang-Yu Yu

      Affiliations

    • Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
    • ,
  • Jenn-Jeih Hsu

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan
    • Director of Taiwan Society of Perinatology, Taipei, Taiwan
    • ,
  • Yang-Hsin Shih

      Affiliations

    • Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
    • Director of Taiwan Epilepsy Society, Taipei, Taiwan
    • ,
  • Chih-Ping Chen

      Affiliations

    • Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
    • Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan

Accepted 27 February 2006.

Article Outline

Summary 

Objective

To present the descriptive statistics of the Taiwanese Registry of Epilepsy and Pregnancy (TREP) for the first 2 years.

Materials and Methods

The pregnancies were recruited from May 2004 to January 2006 with a data format compatible with the International Registry of Antiepileptic Drugs and Pregnancy (EURAP) by referral. The data were collected from either face-to-face interview, telephone interview, or chart review by a research nurse. Five questionnaires (A—E) were required for each pregnancy. The preliminary data for the first 2 years are presented with general descriptive statistics.

Results

Until January 2006, 43 pregnancies have been registered. Questionnaire A was completed in 43 cases, questionnaire B completed in 40 cases, questionnaire C completed in 34 cases, questionnaire D completed in 27 cases, and questionnaire E in eight cases. Among the 39 pregnancies known to take antiepileptic drugs (AEDs) during pregnancy, 28 pregnancies took one AED, nine pregnancies took two AEDs, and two pregnancies took three AEDs. The most commonly used drug was carbamazepine (19/39, 48.72%). Among the 27 pregnancies, who had delivered, the cesarean section rate was 44.44% (12/27), the premature birth rate was 7.41% (2/27), and the fetal malformation rate was 3.7% (1/27).

Conclusion

The preliminary data concluded the efforts of TREP for the first 2 years. Although it is still premature to project a trend out of current data, the registry is expected to provide critical information to local prenatal counseling and contribute further to the international EURAP database.

Key Words:  antiepileptic drugs , epilepsy , EURAP , pregnancy , pregnancy registry , TREP

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References 

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PII: S1028-4559(08)60106-0

doi:10.1016/S1028-4559(08)60106-0

Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 1 , Pages 47-49, March 2007

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