Large Cell Neuroendocrine Carcinoma of the Uterine Cervix Associated with Adenocarcinoma

Ko, Ma-Lee; Jeng, Cherng-Jye; Huang, Shih-Hung; Shen, Jenta; Chen, Su-Chee; Tzeng, Chii-Ruey

doi:10.1016/S1028-4559(08)60111-4

« Previous Next »Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 1 , Pages 68-70, March 2007

Large Cell Neuroendocrine Carcinoma of the Uterine Cervix Associated with Adenocarcinoma

Ma-Lee Ko
- Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan
Cherng-Jye Jeng
- Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan
- Correspondence to: Dr Cherng-Jye Jeng, Department of Obstetrics and Gynecology, Taipei Medical University, 250, Wu-Xin Street, Taipei 110, Taiwan
Shih-Hung Huang
- Department of Pathology, Cathay General Hospital, Taipei, Taiwan
Jenta Shen
- Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, California Pacific Medical Center, San Francisco, USA
Su-Chee Chen
- Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan
Chii-Ruey Tzeng
- Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan

Accepted 14 August 2006.

Summary

Objective

Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma.

Case Report

A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing.