Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 1 , Pages 68-70, March 2007

Large Cell Neuroendocrine Carcinoma of the Uterine Cervix Associated with Adenocarcinoma

  • Ma-Lee Ko

      Affiliations

    • Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan
    • ,
  • Cherng-Jye Jeng

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Cherng-Jye Jeng, Department of Obstetrics and Gynecology, Taipei Medical University, 250, Wu-Xin Street, Taipei 110, Taiwan
    • ,
  • Shih-Hung Huang

      Affiliations

    • Department of Pathology, Cathay General Hospital, Taipei, Taiwan
    • ,
  • Jenta Shen

      Affiliations

    • Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, California Pacific Medical Center, San Francisco, USA
    • ,
  • Su-Chee Chen

      Affiliations

    • Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan
    • ,
  • Chii-Ruey Tzeng

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan

Accepted 14 August 2006.

Article Outline

Summary 

Objective

Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma.

Case Report

A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing.

Conclusion

Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.

Key Words:  adenocarcinoma of the cervix , large cell neuroendocrine carcinoma of the cervix

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References 

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PII: S1028-4559(08)60111-4

doi:10.1016/S1028-4559(08)60111-4

Taiwanese Journal of Obstetrics and Gynecology
Volume 46, Issue 1 , Pages 68-70, March 2007

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