Taiwanese Journal of Obstetrics and Gynecology
Volume 44, Issue 3 , Pages 264-266, September 2005

Caudal Regression Syndrome in the Infant of a Woman with Pregestational Diabetes

  • I-Tsan Huang

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei City Hospital, Branch for Women and Children, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr. I-Tsan Huang, Department of Obstetrics and Gynecology, Taipei City Hospital, Branch for Women and Children, 10 Fucho Street, Taipei 123, Taiwan
    • ,
  • Chi-Chung Chu

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei City Hospital, Branch for Women and Children, Taipei, Taiwan
    • ,
  • Chien-Dai Chiang

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei City Hospital, Branch for Women and Children, Taipei, Taiwan

Department of Neurology, Taipei Medical University, Wan Fang Hospital, Taipei, Taiwan

Received 6 September 2004; received in revised form 27 December 2004; accepted 4 February 2005.

Article Outline

Summary 

Objective

Caudal regression syndrome is a rare congenital anomaly. We report a case of caudal regression syndrome and emphasize the importance of preconception care and periconceptional euglycemic control, which should have been provided much earlier for this diabetic mother.

Case Report

This neonate with caudal regression syndrome was born to a 33-year-old Chinese woman with pregestational diabetes. Postpartum magnetic resonance imaging of this female infant showed agenesis of the lumbosacral spine from L5 and partial agenesis of L4. In spite of being diagnosed with gestational diabetes in her previous third pregnancy, the diabetic mother had received no postpartum follow-up or preconception care in the current pregnancy.

Conclusion

Preconception care and postpartum follow-up for women with diabetes is important. Outpatient preconception care is needed to reduce the risk of major congenital anomalies among the offspring of women with pregestational diabetes mellitus.

Key Words:  caudal regression syndrome , congenital malformation , gestational diabetes , glucose challenge test , preconception care , pregestational diabetes

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References 

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PII: S1028-4559(09)60150-9

doi:10.1016/S1028-4559(09)60150-9

Taiwanese Journal of Obstetrics and Gynecology
Volume 44, Issue 3 , Pages 264-266, September 2005

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