Taiwanese Journal of Obstetrics and Gynecology
Volume 44, Issue 4 , Pages 347-352, December 2005

Management of Oligohydramnios with Antepartum Amnioinfusion, Amniopatch and Cerclage

  • Ming Chen

      Affiliations

    • Department of Obstetrics and Gynecology, and Center for Medical Genetics, Changhua Christian Hospital, Changhua, National Taiwan University Hospital, Taipei, Taiwan, Glasgow, U.K
    • Department of Obstetrics and Gynecology, National Taiwan University Hospital, Glasgow, U.K
    • Corresponding Author InformationCorrespondence to: Dr. Ming Chen, Center for Medical Genetics, Changhua Christian Hospital, 176, Chunghua Road, Changhua 500, Taiwan
  • ,
  • Chang-Yao Hsieh

      Affiliations

    • Department of Obstetrics and Gynecology, National Taiwan University Hospital, Glasgow, U.K
  • ,
  • Alan D. Cameron

      Affiliations

    • Department of Fetal Medicine, Queen Mother's Hospital, Glasgow, U.K
  • ,
  • Jin-Chung Shih

      Affiliations

    • Department of Obstetrics and Gynecology, National Taiwan University Hospital, Glasgow, U.K
  • ,
  • Chien-Nan Lee

      Affiliations

    • Department of Obstetrics and Gynecology, National Taiwan University Hospital, Glasgow, U.K
  • ,
  • Hong-Nerng Ho

      Affiliations

    • Department of Obstetrics and Gynecology, National Taiwan University Hospital, Glasgow, U.K
  • ,
  • Tze-Ho Chen

      Affiliations

    • Department of Obstetrics and Gynecology, and Center for Medical Genetics, Changhua Christian Hospital, Changhua, National Taiwan University Hospital, Taipei, Taiwan, Glasgow, U.K
  • ,
  • Chih-Ping Chen

      Affiliations

    • Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan, Glasgow, U.K

Received 2 September 2005; received in revised form 6 September 2005; accepted 14 September 2005.

Article Outline

Summary 

Objective

To evaluate the efficacy and safety of aggressive management of oligohydramnios.

Methods

Forty women with oligohydramnios (< 30 complete weeks), either because of preterm premature rupture of membranes or with intact membranes, were prospectively enrolled in this study. Eleven women were assigned to the treatment group and 29 to the control group. Transabdominal amnioinfusion was performed with warm Ringer's lactate or normal saline in all 11 patients in the treatment group. In addition, cerclage was performed in patients with ruptured amniotic membranes. Amniopatch was used to salvage a patient with immediate amniorrhea (< 6 hours) after the above procedures.

Results

Nine of the 11 patients prolonged their pregnancy for at least 3 weeks (81.8%), while all 29 patients in the control group delivered their babies within 3 weeks of diagnosis of oligohydramnios (p < 0.05). Signs of maternal infection were noted in two patients in the treatment group (18.2%). The newborns of eight patients in the treatment group survived beyond 1 month (72.7%), whereas this occurred in only six control patients (20.7%; p < 0.05).

Conclusion

Aggressive management seemed to provide prolongation of pregnancy compared with no treatment. Amniopatch salvaged the immediate amniorrhea in our patient.

Key Words:  amnioinfusion , amniopatch , cerclage , oligohydramnios , preterm premature rupture of membranes

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PII: S1028-4559(09)60169-8

doi:10.1016/S1028-4559(09)60169-8

Taiwanese Journal of Obstetrics and Gynecology
Volume 44, Issue 4 , Pages 347-352, December 2005