Taiwanese Journal of Obstetrics and Gynecology
Volume 45, Issue 3 , Pages 215-220, September 2006

Hip Circumference is an Important Predictor of Plasma C-reactive Protein Levels in Overweight and Obese Taiwanese Women

  • Hei-Jen Jou

      Affiliations

    • Department of Obstetrics and Gynecology, Taiwan Adventist Hospital, Taipei, Taiwan
    • Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan
  • ,
  • I-Ping Hsu

      Affiliations

    • Department of Child and Family Studies, Fu-Jen Catholic University, Taipei, Taiwan
  • ,
  • Pei-Ying Ling

      Affiliations

    • Department of Obstetrics and Gynecology, Taiwan Adventist Hospital, Taipei, Taiwan
  • ,
  • Chia-Tzu Lin

      Affiliations

    • Department of Obstetrics and Gynecology, Taiwan Adventist Hospital, Taipei, Taiwan
  • ,
  • Suei-Tsau Tsai

      Affiliations

    • Department of Pediatrics, Taipei, Taiwan
  • ,
  • Hui-Ting Huang

      Affiliations

    • Department of Internal Medicine, Taiwan Adventist Hospital, Taipei, Taiwan
  • ,
  • Shiao-Chi Wu

      Affiliations

    • Institute of Health and Welfare Policy, National Yang-Ming University, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Shiao-Chi Wu, Institute of Health and Welfare Policy, National Yang-Ming University, 155, Section 2, Li-Loung Street, Shih Pai, Taipei 112, Taiwan

Accepted 14 April 2006.

Summary 

Objective

To investigate the relationship between serum levels of C-reactive protein (CRP) with obesity, insulin resistance and metabolic syndrome in overweight or obese Taiwanese women.

Materials and Methods

Analysis was performed on data from 59 overweight or obese women enrolled in a cross-sectional study. Pearson's correlation coefficients were determined between CRP and simple anthropometric indices, fasting insulin, homeostasis model assessment (HOMA) and serum lipid levels. Forward stepwise regression procedure was used to find a “best” subset of predictor variables for CRP.

Results

CRP was found to have significantly positive correlation with body weight, waist circumference, hip circumference, body mass index, log of fasting glucose levels, fasting insulin levels and HOMA. Forward stepwise regression procedure showed that the best predictor for CRP was hip circumference.

Conclusion

The correlation between CRP and insulin resistance or abnormal lipid levels is attributed to their strong correlations with obesity.

Key Words:  body mass index , C-reactive protein , hip circumference , insulin resistance , metabolic syndrome , obesity

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PII: S1028-4559(09)60227-8

doi:10.1016/S1028-4559(09)60227-8

Taiwanese Journal of Obstetrics and Gynecology
Volume 45, Issue 3 , Pages 215-220, September 2006