Taiwanese Journal of Obstetrics and Gynecology
Volume 45, Issue 3 , Pages 230-233, September 2006

Comparison of Day 2 Tubal Embryo Transfer with Day 3 Embryo Transfer into the Uterus of Intracytoplasmic Sperm Injection Derived Human Embryos

  • Tsai-Fang Lee

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Robert Kuo-Kuang Lee

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
    • Division of Reproduction and Endocrinology, Department of Medical Research, Mackay Memorial Hospital, Tamshui, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Robert Kuo-Kuang Lee, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, 92, Section 2, Chung Shan North Road, Taipei 104, Taiwan
  • ,
  • Ming-Huei Lin

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Yuh-Ming Hwu

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Yu-Fen Chih

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Yi-Chun Tsai

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Jin-Tsung Su

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan

Accepted 12 July 2006.

Article Outline

Summary 

Objective

To compare the results of embryo transfer into the uterus (ET) performed on day 3 vs. tubal embryo transfer (TET) on day 2 in couples diagnosed with male factor infertility.

Materials and Methods

We collected data from 34 and 110 patients who underwent intracytoplasmic sperm injection (ICSI) followed by either TET on day 2 or ET on day 3 (January 2001-June 2005), respectively. All couples were diagnosed with male factor infertility; there were no tubal or uterine factors, diminished ovarian reserve, pelvic adhesions, history of polycystic ovary syndrome or previous ovarian surgery.

Results

The clinical pregnancy rates of day 2 TET and day 3 ET following ICSI were 64.71% and 57.27% (p > 0.05), respectively. The corresponding implantation rates were 35.47% and 29.58% (p > 0.05), respectively.

Conclusion

The implantation and clinical pregnancy rates of ET on the 3rd day following ICSI were similar to the rates obtained with TET 2 days after ICSI. Therefore, ET performed 3 days after ICSI should be the first choice for couples with male factor infertility, while day 2 TET remains a good alternative, especially for women with normal tubal function and known difficulties of transcervical ET.

Key Words:  clinical pregnancy rate , embryo transfer , implantation rate , intracytoplasmic sperm injection

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PII: S1028-4559(09)60230-8

doi:10.1016/S1028-4559(09)60230-8

Taiwanese Journal of Obstetrics and Gynecology
Volume 45, Issue 3 , Pages 230-233, September 2006