Concurrent Use of Mifepristone and Misoprostol for Early Medical Abortion

Summary 

Objective

This study was designed to evaluate the efficacy of using mifepristone and misoprostol concurrently for early medical abortion.

Materials and Methods

A total of 90 women with undesired pregnancies ≤ 49 days' gestation were enrolled. All women concurrently received oral mifepristone 200 mg and vaginal misoprostol 800 mg. Follow-up evaluation with transvaginal ultrasonography was performed 4 days and 2 weeks after treatment.

Results

The complete abortion rate was 97.8% (88/90 women). The mean induction to abortion interval was 5.5 hours. The mean bleeding duration was 11.8 days. Patients found the side effects acceptable and reported a 91.1% (82 patients) satisfaction rate.

Conclusion

Concurrent administration of oral mifepristone and vaginal misoprostol is an efficacious regimen for medical abortion of pregnancies ≤ 49 days of gestation.

Key Words:  concurrent medical abortion , mifepristone , misoprostol

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