Taiwanese Journal of Obstetrics and Gynecology
Volume 48, Issue 3 , Pages 232-238 , September 2009

Adenomyosis and Its Variance: Adenomyoma and Female Fertility

  • Peng-Hui Wang

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, National Yang-Ming University Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Peng-Hui Wang, Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, National Yang-Ming University Hospital and National Yang-Ming University, 201, Shih-Pai Road, Section 2, Taipei 112, Taiwan
  • ,
  • Wen-Hsiang Su

      Affiliations

    • Department of Obstetrics and Gynecology, Yee-Zen Hospital, and Institute of Systems Biology and Bioinformatics, National Central University, Tao-Yuan, Taiwan
  • ,
  • Bor-Ching Sheu

      Affiliations

    • Department of Obstetrics and Gynecology, National Taiwan University, National Taiwan University Hospital, Taipei, Taiwan
  • ,
  • Wei-Min Liu

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei Medical University and Taipei Medical University Hospital, Taipei, Taiwan

,Accepted 12 March 2009.

References 

  1. Ozaki T , Takahashi K , Okada M , Kurioka H , Miyazaki K . Live birth after conservative surgery for severe adenomyosis following magnetic resonance imaging and gonadotropin-releasing hormone agonist therapy . Int J Fertil . 1999;44:260–264
  2. Levgur M . Therapeutic opinions for adenomyosis: a review . Arch Gynecol Obstet . 2007;276:1–15
  3. Kepkep K , Tuncay YA , Göynümer G , Tutal E . Transvaginal sonography in the diagnosis of adenomyosis: which findings are most accurate? . Ultrasound Obstet Gynecol . 2007;30:341–345
  4. Fedele L , Bianchi S , Dorta M , Arcaini L , Zanotti F , Carinelli S . Transvaginal ultrasonography in the diagnosis of diffuse adenomyosis . Fertil Steril . 1992;58:94–97
  5. Atzori E , Tronci C , Sionis L . Transvaginal ultrasound in the diagnosis of diffuse adenomyosis . Gynecol Obstet Invest . 1996;42:39–41
  6. Levgur M . Diagnosis of adenomyosis . J Reprod Med . 2007;52:177–193
  7. Matalliotakis IM , Katsikis IK , Panidis DK . Adenomyosis: what is the impact on fertility? . Curr Opin Obstet Gynecol . 2005;17:261–264
  8. Reinhold C , McCarthy S , Bret PM , et al.   Diffuse adenomyosis: comparison of endovaginal US and MR imaging with histopathologic correlation . Radiology . 1996;199:151–158
  9. Chopra S , Lev-Toaff AS , Ors F , Bergin D . Adenomyosis: common and uncommon manifestations on sonography and magnetic resonance imaging . J Ultrasound Med . 2006;25:617–627
  10. Wu MH , Pan HA , Chang FM . Three-dimensional and power Doppler ultrasonography in infertility and reproductive endocrinology . Taiwan J Obstet Gynecol . 2007;46:209–214
  11. Bazot M , Darai E , Rouger J , Detchev R , Cortez A , Uzan S . Limitations of transvaginal sonography for the diagnosis of adenomyosis with histopathological correlation . Ultrasound Obstet Gynecol . 2002;20:605–611
  12. Tamai K , Togashi K , Ito T , Morisawa N , Fujiwara T , Koyama T . MR imaging findings of adenomyosis: correlation with histopathologic features and diagnostic pitfalls . Radiographics . 2005;25:21–40
  13. Jeng CJ , Huang SH , Shen J , Chou CS , Tzeng CR . Laparoscopy-guided myometrial biopsy in the definite diagnosis of diffuse adenomyosis . Hum Reprod . 2007;22:2016–2019
  14. Wang PH , Fuh JL , Chao HT , Liu WM , Cheng MH , Chao KC . Is the surgical approach beneficial to subfertile women with symptomatic extensive adenomyosis? . J Obstet Gynaecol Res . 2009;35:495–502
  15. Wang PH , Lee WL , Cheng MH , Yen MS , Chao KC , Chao HT . Use of a gonadotropin-releasing hormone agonist to manage perimenopausal women with symptomatic uterine myomas . Taiwan J Obstet Gynecol . 2009;48:133–137
  16. Liu WM , Wang PH , Tang WL , Wang IT , Tzeng CR . Uterine artery ligation for treatment of pregnant women with uterine leiomyomas who are undergoing cesarean section . Fertil Steril . 2006;86:423–428
  17. Kim MD , Kim NK , Kim HJ , Lee MH . Pregnancy following uterine artery embolization with polyvinyl alcohol particles for patients with uterine fibroid or adenomyosis . Cardiovasc Intervent Radiol . 2005;28:611–615
  18. Owolabi TO , Strickler RC . Adenomyosis: a neglected diagnosis . Obstet Gynecol . 1977;50:424–427
  19. Siegler AM . Adenomyosis . J Reprod Med . 1994;39:841–853
  20. Wood C . Surgical and medical treatment of adenomyosis . Hum Reprod Update . 1998;4:323–336
  21. Devlieger R , D'Hooghe T , Timmerman D . Uterine adenomyosis in the infertility clinic . Hum Reprod Update . 2003;9:139–147
  22. Honore LH , Cumming DC , Dunlop DL , Scott JZ . Uterine adenomyoma associated with infertility: a report of three cases . J Reprod Med . 1988;33:331–335
  23. Grow DR , Filer RB . Treatment of adenomyosis with long-term GnRH analogues: a case report . Obstet Gynecol . 1991;78:538–539
  24. Hirata JD , Moghissi KS , Ginsburg KA . Pregnancy after medical therapy of adenomyosis with gonadotropin-releasing hormone agonist . Fertil Steril . 1993;59:444–445
  25. Nelson JR , Corson SL . Long-term management of adenomyosis with a gonadotropin-releasing hormone agonist . Fertil Steril . 1993;59:441–443
  26. Wood C , Maher P , Hill D . Biopsy diagnosis and conservative surgical treatment of adenomyosis . Aust N Z J Obstet Gynaecol . 1993;33:319–321
  27. Silva PD , Perkins HE , Schauberger CW . Live birth after treatment of severe adenomyosis with a gonadotropin-releasing hormone agonist . Fertil Steril . 1994;61:171–172
  28. Wood C , Maher P , Hill D . Biopsy diagnosis and conservative surgical treatment of adenomyosis . J Am Assoc Gynecol Laparosc . 1994;1:313–316
  29. Huang WH , Yang TS , Yuan CC . Successful pregnancy after treatment of deep adenomyosis with cytoreductive surgery and subsequent gonadotropin-releasing hormone agonist: a case report . Zhonghua Yi Xue Za Zhi (Taipei) . 1998;61:726–729
  30. Huang FJ , Kung FT , Chang SY , Hsu TY . Effects of short-course buserelin therapy on adenomyosis: a report of two cases . J Reprod Med . 1999;44:741–744
  31. Lin J , Sun C , Zheng H . Gonadotropin-releasing hormone agonists and laparoscopy in the treatment of adenomyosis with infertility . Chin Med J (Engl) . 2000;113:442–445
  32. Wang PH , Yang TS , Lee WL , Chao HT , Chang SP , Yuan CC . Treatment of infertile women with adenomyosis with a conservative microsurgical technique and a gonadotropin-releasing hormone agonist . Fertil Steril . 2000;73:1061–1062
  33. Wang CJ , Yuen LT , Chang SD , Lee CL , Soong YK . Use of laparoscopic cytoreductive surgery to treat infertile women with localized adenomyosis . Fertil Steril . 2006;86:462.e5–462.e8
  34. Rabinovici J , Inbar Y , Eylon SC , Schiff E , Hananel A , Freundlich D . Pregnancy and live birth after focused ultrasound surgery for symptomatic focal adenomyosis: a case report . Hum Reprod . 2006;21:1255–1259
  35. Cheng MH , Chao HT , Wang PH . Medical treatment for uterine myomas . Taiwan J Obstet Gynecol . 2008;47:18–23
  36. Lee WL , Liu RS , Yuan CC , Chao HT , Wang PH . Relationship between gonadotropin-releasing hormone agonist and myoma cellular activity: preliminary findings on positron emission tomography . Fertil Steril . 2001;75:638–639
  37. Chia CC , Huang SC , Chen SS , et al.   Ultrasonographic evaluation of the uterine fibroids induced by treatment with a GnRH analog . Taiwan J Obstet Gynecol . 2006;45:124–128
  38. Parsanezhad ME, Azmoon M, Alborzi S, et al. A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status. Fertil Steril doi: 10.1016/j.fertnstert.2008.09.064 (In press).
  39. Wilson AC , Meethal SV , Bowen RL , Atwood CS . Leuprolide acetate: a drug of diverse clinical applications . Expert Opin Investig Drugs . 2007;16:1851–1863
  40. Cheng MH , Wang PH . Uterine myoma: a condition amendable to medical therapy? . Expert Opin Emerg Drugs . 2008;13:119–133
  41. Ravina JH, Herbreteau D, Ciraru-Vigneron N, Bouret JM, Houdart E, Aymard A, et al. Arterial embolisation to treat uterine myomata . Lancet . 1995;346:671–672
  42. Rabinovici J , Stewart EA . New interventional techniques for adenomyosis . Best Pract Res Clin Obstet Gynaecol . 2006;20:617–636
  43. Simsek M , Sadik S , Taskin O , et al.   Role of laparoscopic uterine artery coagulation in management of symptomatic myomas: a prospective study using ultrasound and magnetic resonance imaging . J Minim Invasive Gynecol . 2006;13:315–319
  44. Liu WM , Wang PH , Chou CS , Tang WL , Wang IT , Tzeng CR . Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas . Fertil Steril . 2007;87:356–361
  45. Wang PH , Liu WM , Fuh JL , Chao HT , Chao KC , Yuan CC . Laparoscopic uterine vessel occlusion in the management of women with symptomatic uterine myomas with and without adding laparoscopic myomectomy: 4-year results . J Minim Invasive Gynecol . 2008;15:712–718
  46. Holub Z , Mara M , Kuzel D , Jabor A , Maskova J , Eim J . Pregnancy outcomes after uterine artery occlusion: prospective multicentric study . Fertil Steril . 2008;90:1886–1891
  47. Wang PH , Liu WM , Fuh JL , Chao HT , Yuan CC , Chao KC . Symptomatic myoma treated with laparoscopic uterine vessel occlusion and subsequent immediate myomectomy: which is the optimal surgical approach? . Fertil Steril . 2009;92:762–769
  48. Liu WM , Tzeng CR , Yi-Jen C , Wang PH . Combining the uterine depletion procedure and myomectomy may be useful for treating symptomatic fibroids . Fertil Steril . 2004;82:205–210
  49. Siskin GP , Tublin ME , Stainken BF , Dowling K , Dolen EG . Uterine artery embolization for the treatment of adenomyosis: clinical response and evaluation with MR imaging . AJR Am J Roentgenol . 2001;177:297–302
  50. Mara M , Maskova J , Fucikova Z , Kuzel D , Belsan T , Sosna O . Midterm clinical and first reproductive results of a randomized controlled trial comparing uterine fibroid embolization and myomectomy . Cardiovasc Intervent Radiol . 2008;31:73–85
  51. American College of Obstetricians and Gynecologists  . ACOG Committee Opinion no. 293: uterine artery embolization . Obstet Gynecol . 2004;103:403–404
  52. Goldberg J , Pereira L . Pregnancy outcomes following treatment for fibroids: uterine fibroid embolization versus laparoscopic myomectomy . Curr Opin Obstet Gynecol . 2006;18:402–406
  53. Wang PH , Liu WM , Fuh JL , Cheng MH , Chao HT . Comparison of surgery alone and combined surgical-medical treatment in the management of symptomatic uterine adenomyoma . Fertil Steril . 2009;92:876–885
  54. Yen MS , Yang TS , Yu KJ , Wang PH . Comments on laparoscopic excision of myometrial adenomyomas in patients with adenomyosis uteri and main symptoms of severe dysmenorrhea and hypermenorrhea . J Am Assoc Gynecol Laparosc . 2004;11:441–442
  55. Vercellini P , Maddalena S , De Giorgi O , Aimi G , Crosignani PG . Abdominal myomectomy for infertility: a comprehensive review . Hum Reprod . 1998;13:873–879
  56. Fujishita A , Masuzaki H , Khan KN , Kitajima M , Ishimaru T . Modified reduction surgery for adenomyosis: a preliminary report of the transverse H incision technique . Gynecol Obstet Invest . 2004;57:132–138
  57. Strizhakov AN , Davydov AI . Myometrectomy—a method of choice for the therapy of adenomyosis patients in the reproductive period . Akush Ginekol (Mosk) . 1995;(5):31–33 [In Russian]

 This paper was presented at the 96th Annual Meeting of the Taiwan Association of Obstetrics and Gynecology, Taipei, Taiwan, March 24–25, 2007

PII: S1028-4559(09)60295-3

doi: 10.1016/S1028-4559(09)60295-3

Taiwanese Journal of Obstetrics and Gynecology
Volume 48, Issue 3 , Pages 232-238 , September 2009