Taiwanese Journal of Obstetrics and Gynecology
Volume 48, Issue 3 , Pages 254-257, September 2009

Age and Prevalence of Cervical Carcinoma in Subsequent Hysterectomy Following a Conization Procedure

  • Ting-Hung Wun

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan
    • ,
  • Will Wei-Cheng Chiu

      Affiliations

    • Department of Obstetrics and Gynecology, Chang-Bing Show Chwan Memorial Hospital, Changhua, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Will Wei-Cheng Chiu, Department of Obstetrics and Gynecology, Chang-Bing Show Chwan Memorial Hospital, 6, Lu-Gong Road, LuGang Township, Chang Hwa County, Taiwan
    • ,
  • Chen-Bin Wang

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan
    • ,
  • Ching-Cheng Tseng

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan
    • ,
  • Chun-Hung Chen

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan
    • ,
  • Yu-Hsiang Lin

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan
    • ,
  • Chung-Yuan Lee

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan
    • ,
  • Ying-Lun Sun

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan
    • ,
  • Chih-Jen Tseng

      Affiliations

    • Department of Obstetrics and Gynecology Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Changhua, Taiwan

Accepted 24 July 2008.

Article Outline

Summary 

Objective

To determine the prevalence and age of patients with cervical carcinoma missed by a loop electrosurgical excision procedure.

Materials and Methods

A total of 253 women with cervical dysplasia who underwent conization and 248 women who later underwent hysterectomy were retrospectively reviewed. The age and prevalence of those with cervical carcinoma diagnosed and missed by conization were determined.

Results

Of the 248 patients, 11 cases (4.4%) of cervical carcinoma were missed by cervical conization. The age of those with cervical carcinoma missed by conization was significantly greater than those whose diagnosis was not missed (p < 0.05).

Conclusion

Women with severe cervical dysplasia who no longer wish to preserve fertility should be advised to undergo hysterectomy if the conization margins are not free of disease. Older women with incomplete resection margins tend to have undiagnosed hidden cervical carcinoma after cervical conization.

Key Words:  cervical intraepithelial neoplasia , cervix cancer , conization , electrosurgery , hysterectomy

No full text is available. To read the body of this article, please view the PDF online.

 

Back to Article Outline

References 

  1. Walboomers JM , Jacobs MV , Manos MM , et al.   Human papillomavirus is a necessary cause of invasive cervical cancer worldwide . J Pathol . 1999;189:12–19
  2. World Health Organization  . Fact Sheet No. 297, February 2006: Cancer . Available at: http://www.who.int/mediacentre/factsheets/fs297/en/index.html [Date accessed 1 December 2007]
  3. Canavan TP , Doshi NR . Cervical cancer . Am Fam Physician . 2000;61:1369–1376
  4. Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, et al. Cancer statistics, 2006 . CA Cancer J Clin . 2006;56:106–130
  5. Natee J , Therasakvichaya S , Boriboonhirunsarn D . Prevalence and risk factors for residual cervical neoplasia in subsequent hysterectomy following LEEP or conization . J Med Assoc Thai . 2005;88:1344–1348
  6. Husseinzadeh N , Shbaro I , Wesseler T . Predictive value of cone margins and post-cone endocervical curettage with residual disease in subsequent hysterectomy . Gynecol Oncol . 1989;33:198–200
  7. Phelps JY , Ward JA , Szigeti J , Bowland CH , Mayer AR . Cervical cone margins as a predictor for residual dysplasia in post-cone hysterectomy specimens . Obstet Gynecol . 1994;84:128–130
  8. Benedet JL , Anderson GH , Boyes DA . Colposcopic accuracy in the diagnosis of microinvasive and occult invasive carcinoma of the cervix . Obstet Gynecol . 1985;65:557–562
  9. Berek JS . Anatomy and Embryology . In: Berek and Novak's Gynecology . 14th edition. Philadelphia: Lippincott Williams & Wilkins; 2006;p. 105–107
  10. Moore BC , Higgins RV , Laurent SL , Marroum MC , Bellitt P . Predictive factors from cold knife conization for residual cervical intraepithelial neoplasia in subsequent hysterectomy . Am J Obstet Gynecol . 1995;173:361–368
  11. Kalogirou D , Antoniou G , Karakitsos P , Botsis D , Kalogirou O , Giannikos L . Predictive factors used to justify hysterectomy after loop conization: increasing age and severity of disease . Eur J Gynaecol Oncol . 1997;18:113–116

PII: S1028-4559(09)60299-0

doi:10.1016/S1028-4559(09)60299-0

Taiwanese Journal of Obstetrics and Gynecology
Volume 48, Issue 3 , Pages 254-257, September 2009

Article Tools