Taiwanese Journal of Obstetrics and Gynecology
Volume 48, Issue 4 , Pages 356-369 , December 2009

Unique Biological Properties and Application Potentials of CD34+ CD38− Stem Cells From Various Sources

  • Tao-Yeuan Wang

      Affiliations

    • Department of Pathology, Mackay Memorial Hospital, Taipei, Taiwan
    • Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    • ,
  • Shing-Jyh Chang

      Affiliations

    • Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Hsinchu, Taipei, Taiwan
    • National Tsing Hua University, Hsinchu, Taipei, Taiwan
    • Co-first author
    • ,
  • Margaret Dah-Tsyr Chang

      Affiliations

    • National Tsing Hua University, Hsinchu, Taipei, Taiwan
    • ,
  • Hsei-Wei Wang

      Affiliations

    • Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan
    • VGH-YM Genome Center, National Yang-Ming University, Taipei, Taiwan
    • Department of Education and Research, Taipei City Hospital, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Hsei-Wei Wang, Institute of Microbiology and Immunology, National Yang-Ming University, 155, Section 2, Li-Nong Street, Taipei, Taiwan

,Accepted 9 March 2009.

References 

  1. Brunstein CG , Baker KS , Wagner JE . Umbilical cord blood transplantation for myeloid malignancies . Curr Opin Hematol . 2007;14:162–169
  2. Ng YY, van Kessel B, Lokhorst HM, Baert MR, van den Burg CM, Bloem AC, et al. Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity . J Leukoc Biol . 2004;75:314–323
  3. Oswald J , Steudel C , Salchert K , et al.   Gene-expression profiling of CD34+ hematopoietic cells expanded in a collagen I matrix . Stem Cells . 2006;24:494–500
  4. Ivanova NB , Dimos JT , Schaniel C , Hackney JA , Moore KA , Lemischka IR . A stem cell molecular signature . Science . 2002;298:601–604
  5. Loges S , Fehse B , Brockmann MA , et al.   Identification of the adult human hemangioblast . Stem Cells Dev . 2004;13:229–242
  6. Jaatinen T , Hemmoranta H , Hautaniemi S , et al.   Global gene expression profile of human cord blood-derived CD133+ cells . Stem Cells . 2006;24:631–641
  7. Georgantas RW , Tanadve V , Malehorn M , et al.   Microarray and serial analysis of gene expression analyses identify known and novel transcripts overexpressed in hematopoietic stem cells . Cancer Res . 2004;64:4434–4441
  8. Featherstone DE , Broadie K . Wrestling with pleiotropy: genomic and topological analysis of the yeast gene expression network . Bioessays . 2002;24:267–274
  9. Jen CH, Manfield IW, Michalopoulos I, Pinney JW, Willats WG, Gilmartin PM, et al. The Arabidopsis co-expression tool (ACT): a WWW-based tool and database for microarray-based gene expression analysis . Plant J . 2006;46:336–348
  10. Chang SJ , Huang TS , Wang KL , et al.   Genetic network analysis of human CD34+ hematopoietic stem/precursor cells . Taiwan J Obstet Gynecol . 2008;47:422–430
  11. Wang HW , Trotter MW , Lagos D , et al.   Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma . Nat Genet . 2004;36:687–693
  12. Dennis G, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery . Genome Biol . 2003;4:P3
  13. Huang TS , Hsieh JY , Wu YH , et al.   Functional network reconstruction reveals somatic stemness genetic maps and dedifferentiation-like transcriptome reprogramming induced by GATA2 . Stem Cells . 2008;26:1186–1201
  14. Malcles MH, Wang HW, Koumi A, Tsai YH, Yu M, Godfrey A, et al. Characterisation of the anti-apoptotic function of survivin-Δ Ex3 during TNFα-mediated cell death . Br J Cancer . 2007;96:1659–1666
  15. Elagib KE , Racke FK , Mogass M , Khetawat R , Delehanty LL , Goldfarb AN . RUNX1 and GATA-1 coexpression and co operation in megakaryocytic differentiation . Blood . 2003;101:4333–4341
  16. Khanna C , Wan X , Bose S , et al.   The membrane-cytoskele ton linker ezrin is necessary for osteosarcoma metastasis . Nat Med . 2004;10:182–186
  17. Yu Y , Khan J , Khanna C , Helman L , Meltzer PS , Merlino G . Expression profiling identifies the cytoskeletal organizerezrin and the developmental homeoprotein Six-1 as key metastatic regulators . Nat Med . 2004;10:175–181
  18. Harris MA , Clark J , Ireland A , et al.   The Gene Ontology (GO) database and informatics resource . Nucleic Acids Res . 2004;32:D258–D261
  19. Kawabata H, Germain RS, Ikezoe T, Tong X, Green EM, Gombart AF, et al. Regulation of expression of murine transferrin receptor 2 . Blood . 2001;98:1949–1954
  20. Crossley M , Tsang AP , Bieker JJ , Orkin SH . Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1 . J Biol Chem . 1994;269:15440–15444
  21. Barabasi AL , Oltvai ZN . Network biology: understanding the cell's functional organization . Nat Rev Genet . 2004;5:101–113
  22. Janes KA , Yaffe MB . Data-driven modelling of signal-transduction networks . Nat Rev Mol Cell Biol . 2006;7:820–828

PII: S1028-4559(09)60324-7

doi: 10.1016/S1028-4559(09)60324-7

Taiwanese Journal of Obstetrics and Gynecology
Volume 48, Issue 4 , Pages 356-369 , December 2009

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